The pretty reality-tv-starlet-turned-model stars alongside fellow model Simon Nessman in a campaign shot by photographer Alasdair McLellan and styled by Melanie Ward.
It's the second major coup for the brand, who recently made headlines featuring a buff and tattooed Justin Bieber next to supermodel Lara Stone in their Spring 2015 denim campaign.
Interestingly, Bieber and Jenner are known besties, and part of the next-gen Hollywood 'Brat Pack' also containing model Gigi Hadid.
Calvin Klein Jeans has always had a knack for creating controversy with their denim campaigns - past recruits include an underage Brooke Shields and a baby-faced topless Kate Moss.
We're sure modelling for the iconic denim brand is just one of many more career highlights to come for Kendall Jenner.
The limited-edition logo-heavy Denim Series is set to drop in stores globally on April 15. The youthful male and female collection features modern pieces with sport-inspired details.